EGFR Kinase Promotes Acquisition of Stem Cell-Like Properties: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma Stem Cells

Members of the EGFR/ErbB family of tyrosine kinases are found to be highly expressed and deregulated in many cancers, including head and neck squamous cell carcinoma (HNSCC). The ErbB family, including EGFR, has been demonstrated to play key roles in metastasis, tumorigenesis, cell proliferation, an...

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Главные авторы: Abhold, Eric L., Kiang, Alan, Rahimy, Elham, Kuo, Selena Z., Wang-Rodriguez, Jessica, Lopez, Jay Patrick, Blair, Katherine J., Yu, Michael Andrew, Haas, Martin, Brumund, Kevin T., Altuna, Xabier, Patel, Andrew, Weisman, Robert A., Ongkeko, Weg M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288103/
https://ncbi.nlm.nih.gov/pubmed/22384257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032459
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