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Aging phenotype(s) in kidneys of diabetic mice are p66ShcA dependent
The p66ShcA protein controls cellular responses to oxidative stress, senescence, and apoptosis. Here, we test the hypothesis that aging phenotype(s) commonly associated with the broad category of chronic kidney disease are accelerated in diabetic kidneys and linked to the p66ShcA locus. At the organ...
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| Pubblicato in: | Am J Physiol Renal Physiol |
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| Autori principali: | , , , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6336986/ https://ncbi.nlm.nih.gov/pubmed/30207172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00608.2017 |
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