Periostin overexpression in collecting ducts accelerates renal cyst growth and fibrosis in polycystic kidney disease

In polycystic kidney disease (PKD), persistent activation of cell proliferation and matrix production contributes to cyst growth and fibrosis, leading to progressive deterioration of renal function. Previously, we showed that periostin, a matricellular protein involved in tissue repair, is overexpre...

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Bibliografiska uppgifter
I publikationen:Am J Physiol Renal Physiol
Huvudupphovsmän: Raman, Archana, Parnell, Stephen C., Zhang, Yan, Reif, Gail A., Dai, Yuqiao, Khanna, Aditi, Daniel, Emily, White, Corey, Vivian, Jay L., Wallace, Darren P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336984/
https://ncbi.nlm.nih.gov/pubmed/30332313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00246.2018
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