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Sepiapterin alleviates impaired gastric nNOS function in spontaneous diabetic female rodents through NRF2 mRNA turnover and miRNA biogenesis pathway

An impaired nitrergic system and altered redox signaling contribute to gastric dysmotility in diabetics. Our earlier studies show that NF-E2-related factor 2 (NRF2) and phase II antioxidant enzymes play a vital role in gastric neuronal nitric oxide synthase (nNOS) function. This study aims to invest...

詳細記述

保存先:
書誌詳細
出版年:Am J Physiol Gastrointest Liver Physiol
主要な著者: Gangula, Pandu R., Challagundla, Kishore B., Ravella, Kalpana, Mukhopadhyay, Sutapa, Chinnathambi, Vijayakumar, Mittal, Mukul K., Sekhar, K. Raja, Sampath, Chethan
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336949/
https://ncbi.nlm.nih.gov/pubmed/30285465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00152.2018
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