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Sepiapterin reverses the changes in gastric nNOS dimerization and function in diabetic gastroparesis

BACKGROUND: We have demonstrated previously that in vivo supplementation of tetrahydrobiopterin (BH(4)); a co-factor for neuronal nitric oxide synthase (nNOS) significantly restored delayed gastric emptying and attenuated nitrergic relaxation in diabetic rat. In this study, we have investigated whet...

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Detalhes bibliográficos
Main Authors: GANGULA, P. R. R., MUKHOPADHYAY, S., PASRICHA, P. J., RAVELLA, K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072796/
https://ncbi.nlm.nih.gov/pubmed/20731778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2010.01588.x
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