O-GlcNAcylation promotes colorectal cancer metastasis via the miR-101-O-GlcNAc/EZH2 regulatory feedback circuit

Advanced colorectal cancer (CRC) is one of the deadliest cancers, and the 5-year survival rate of patients with metastasis is extremely low. The epithelial–mesenchymal transition (EMT) is considered essential for metastatic CRC, but the fundamental molecular basis underlying this effect remains unkn...

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Pubblicato in:Oncogene
Autori principali: Jiang, Mingzuo, Xu, Bing, Li, Xiaowei, Shang, Yulong, Chu, Yi, Wang, Weijie, Chen, Di, Wu, Nan, Hu, Sijun, Zhang, Song, Li, Mengbin, Wu, Kaichun, Yang, Xiaoyong, Liang, Jie, Nie, Yongzhan, Fan, Daiming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336687/
https://ncbi.nlm.nih.gov/pubmed/30093632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0435-5
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