Loss of function of NF1 is a mechanism of acquired resistance to endocrine therapy in lobular breast cancer

BACKGROUND: Invasive lobular carcinoma (ILC) as a disease entity distinct from invasive ductal carcinoma (IDC) has merited focused studies of the genomic landscape, but those to date are largely limited to the assessment of early-stage cancers. Given that genomic alterations develop as acquired resi...

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Bibliographic Details
Published in:	Ann Oncol
Main Authors:	Sokol, E S, Feng, Y X, Jin, D X, Basudan, A, Lee, A V, Atkinson, J M, Chen, J, Stephens, P J, Frampton, G M, Gupta, P B, Ross, J S, Chung, J H, Oesterreich, S, Ali, S M, Hartmaier, R J
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 2019
Subjects:	Original Articles
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6336006/ https://ncbi.nlm.nih.gov/pubmed/30423024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdy497
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Loss of function of NF1 is a mechanism of acquired resistance to endocrine therapy in lobular breast cancer

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