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Antifibrotic therapy disrupts stromal barriers and modulates the immune landscape in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDA) remains one of the deadliest forms of cancer, in part, because it is largely refractory to current therapies. The failure of most standard therapies in PDA, as well as promising immune therapies, may be largely ascribed to highly unique and protective stromal m...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Res
Hauptverfasser: Elahi-Gedwillo, Kianna Y., Carlson, Marjorie, Zettervall, Jon, Provenzano, Paolo P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335156/
https://ncbi.nlm.nih.gov/pubmed/30401713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-1334
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