Identification and functional characterization of CD8(+) T regulatory cells in type 1 diabetes patients

Type 1 diabetes is an autoimmune disease where autoreactive T lymphocytes destroy pancreatic beta cells. We previously reported a defect in CD4(+) Tregs cell proliferation and reduced CD4(+) Tregs PD-1 expression in patients. Another ‘memory-like’ regulatory subset, CD8(+) Tregs, evaluated as CD8(+)...

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Vydáno v:PLoS One
Hlavní autoři: Pellegrino, Marsha, Crinò, Antonino, Rosado, Manuela M., Fierabracci, Alessandra
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334945/
https://ncbi.nlm.nih.gov/pubmed/30650147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210839
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