Identification of GAD65 AA 114-122 reactive 'memory-like' NK cells in newly diagnosed Type 1 diabetic patients by HLA-class I pentamers

Type 1 diabetes is an autoimmune disease, in which pancreatic β cells are destroyed by autoreactive T cells in genetically predisposed individuals. Serum beta cell autoantibody specificities have represented the mainstay for classifying diabetes as autoimmune-mediated and for stratifying risk in fir...

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Publicat a:PLoS One
Autors principals: Perri, Valentina, Gianchecchi, Elena, Cifaldi, Loredana, Pellegrino, Marsha, Giorda, Ezio, Andreani, Marco, Cappa, Marco, Fierabracci, Alessandra
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728516/
https://ncbi.nlm.nih.gov/pubmed/29236750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189615
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