OTUB2 stabilizes U2AF2 to promote the Warburg effect and tumorigenesis via the AKT/mTOR signaling pathway in non-small cell lung cancer

Increasing evidence has confirmed that deubiquitinating enzymes play an important role in lung cancer progression. In the current study, we investigated the expression profile of deubiquitinating enzymes in non-small cell lung cancer (NSCLC) tissues and identified OTUB2 as an upregulated deubiquitin...

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Vydáno v:Theranostics
Hlavní autoři: Li, Jing, Cheng, Dongdong, Zhu, Miaoxin, Yu, Huajian, Pan, Zhen, Liu, Lei, Geng, Qin, Pan, Hongyu, Yan, Mingxia, Yao, Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6332791/
https://ncbi.nlm.nih.gov/pubmed/30662561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.29545
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