Učitavanje...
NHA2 promotes cyst development in an in vitro model of polycystic kidney disease
KEY POINTS: Significant and selective up‐regulation of the Na(+)/H(+) exchanger NHA2 (SLC9B2) was observed in cysts of patients with autosomal dominant polycystic kidney disease. Using the MDCK cell model of cystogenesis, it was found that NHA2 increases cyst size. Silencing or pharmacological inhib...
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| Izdano u: | J Physiol |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6332743/ https://ncbi.nlm.nih.gov/pubmed/30242840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276796 |
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