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Unconventional Chemiosmotic Coupling of NHA2, a Mammalian Na(+)/H(+) Antiporter, to a Plasma Membrane H(+) Gradient

Human NHA2, a newly discovered cation proton antiporter, is implicated in essential hypertension by gene linkage analysis. We show that NHA2 mediates phloretin-sensitive Na(+)-Li(+) counter-transport (SLC) activity, an established marker for hypertension. In contrast to bacteria and fungi where H(+)...

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Hlavní autoři: Kondapalli, Kalyan C., Kallay, Laura M., Muszelik, Melanie, Rao, Rajini
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476291/
https://ncbi.nlm.nih.gov/pubmed/22948142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.403550
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