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A human Na(+)/H(+) antiporter sharing evolutionary origins with bacterial NhaA may be a candidate gene for essential hypertension

Phylogenetic analysis of the cation/proton antiporter superfamily has uncovered a previously unknown clade of genes in metazoan genomes, including two previously uncharacterized human isoforms, NHA1 and NHA2, found in tandem on human chromosome 4. The NHA (sodium hydrogen antiporter) family members...

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Détails bibliographiques
Auteurs principaux: Xiang, Minghui, Feng, Mingye, Muend, Sabina, Rao, Rajini
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141836/
https://ncbi.nlm.nih.gov/pubmed/18000046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707120104
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