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Unconventional Chemiosmotic Coupling of NHA2, a Mammalian Na(+)/H(+) Antiporter, to a Plasma Membrane H(+) Gradient
Human NHA2, a newly discovered cation proton antiporter, is implicated in essential hypertension by gene linkage analysis. We show that NHA2 mediates phloretin-sensitive Na(+)-Li(+) counter-transport (SLC) activity, an established marker for hypertension. In contrast to bacteria and fungi where H(+)...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3476291/ https://ncbi.nlm.nih.gov/pubmed/22948142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.403550 |
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