Nitric Oxide-Releasing Aspirin Suppresses NF-κB Signaling in Estrogen Receptor Negative Breast Cancer Cells in Vitro and in Vivo

Estrogen receptor negative (ER(−)) breast cancer is aggressive, responds poorly to current treatments and has a poor prognosis. The NF-κB signaling pathway is implicated in ER(−) tumorigenesis. Aspirin (ASA) is chemopreventive against ER(+) but not for ER(−) breast cancers. Nitric oxide-releasing as...

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Veröffentlicht in:Molecules
Hauptverfasser: Nath, Niharika, Chattopadhyay, Mitali, Rodes, Deborah B., Nazarenko, Anna, Kodela, Ravinder, Kashfi, Khosrow
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331965/
https://ncbi.nlm.nih.gov/pubmed/26184135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules200712481
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