Localized immune tolerance from FasL-functionalized PLG scaffolds

Intraportal allogeneic islet transplantation has been demonstrated as a potential therapy for type 1 diabetes (T1D). The placement of islets into the liver and chronic immunosuppression to control rejection are two major limitations of islet transplantation. We hypothesize that localized immunomodul...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Skoumal, Michael, Woodward, Kyle B., Zhao, Hong, Wang, Feng, Yolcu, Esma S., Pearson, Ryan M., Hughes, Kevin R., García, Andrés J., Shea, Lonnie D., Shirwan, Haval
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331284/
https://ncbi.nlm.nih.gov/pubmed/30458362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.11.015
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