Wordt geladen...

Overcoming drug resistance through the development of selective inhibitors of UDP-glucuronosyltransferase enzymes

Drug resistance is a major cause of cancer-related mortality. Glucuronidation of drugs via elevation of UDP-glucuronosyltransferases (UGT1As) correlates with clinical resistance. The nine UGT1A family members have broad substrate specificities attributed to their variable N-terminal domains and shar...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Mol Biol
Hoofdauteurs: Osborne, Michael J., Coutinho de Oliveira, Luciana, Volpon, Laurent, Zahreddine, Hiba Ahmad, Borden, Katherine L.B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331242/
https://ncbi.nlm.nih.gov/pubmed/30428301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.11.007
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!