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Intrinsic dynamics of a human gene reveal the basis of expression heterogeneity
Transcriptional regulation in metazoans occurs through long range genomic contacts between enhancers and promoters, and most genes are transcribed in episodic ‘bursts’ of RNA synthesis. To understand the relationship between these two phenomena and the dynamic regulation of genes in response to upst...
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| Publicat a: | Cell |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6331006/ https://ncbi.nlm.nih.gov/pubmed/30554876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.11.026 |
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