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Common Cancer-Driver Mutations and their Association with Abnormally Methylated Genes in Lung Adenocarcinoma from Never-Smokers

OBJECTIVES: Lung adenocarcinoma in never-smokers accounts for 15–20% of all lung cancer. Although targetable mutations are more prevalent in these tumors, the biological and clinical importance of coexisting and/or mutually exclusive abnormalities is just emerging. This study evaluates the relations...

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Vydáno v:Lung Cancer
Hlavní autoři: Tessema*, Mathewos, Rossi, Michael R., Picchi, Maria A., Yingling, Christin M., Lin, Yong, Ramalingam, Suresh S., Belinsky, Steven A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331003/
https://ncbi.nlm.nih.gov/pubmed/30089603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2018.07.011
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