Spectrum of Oncogenic Driver Mutations in Lung Adenocarcinomas from East Asian Never Smokers

PURPOSE: We previously showed that 90% (47 of 52; 95% CI, 0.79 to 0.96) of lung adenocarcinomas from East Asian never-smokers harbored well-known oncogenic mutations in just four genes: EGFR, HER2, ALK, and KRAS. Here, we sought to extend these findings to more samples and identify driver alteration...

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Detalhes bibliográficos
Main Authors: Li, Chenguang, Fang, Rong, Sun, Yihua, Han, Xiangkun, Li, Fei, Gao, Bin, Iafrate, A. John, Liu, Xin-Yuan, Pao, William, Chen, Haiquan, Ji, Hongbin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227646/
https://ncbi.nlm.nih.gov/pubmed/22140546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028204
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