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Kinetics and MR-Based Monitoring of AAV9 Vector Delivery into Cerebrospinal Fluid of Nonhuman Primates
Here we evaluated the utility of MRI to monitor intrathecal infusions in nonhuman primates. Adeno-associated virus (AAV) spiked with gadoteridol, a gadolinium-based MRI contrast agent, enabled real-time visualization of infusions delivered either via cerebromedullary cistern, lumbar, cerebromedullar...
में बचाया:
| में प्रकाशित: | Mol Ther Methods Clin Dev |
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| मुख्य लेखकों: | , , , , , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society of Gene & Cell Therapy
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6330508/ https://ncbi.nlm.nih.gov/pubmed/30666308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.12.001 |
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