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Engineering and Design of Chimeric Antigen Receptors

T cells engineered with chimeric antigen receptors (CARs) have emerged as a potent new class of therapeutics for cancer, based on their remarkable potency in blood cancers. Since the first clinical reports of their efficacy emerged 7 years ago, investigators have focused on the mechanisms and proper...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Ther Methods Clin Dev
Prif Awduron: Guedan, Sonia, Calderon, Hugo, Posey, Avery D., Maus, Marcela V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Gene & Cell Therapy 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330382/
https://ncbi.nlm.nih.gov/pubmed/30666307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.12.009
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