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Relative impact of indels versus SNPs on complex disease

It is unclear whether insertions and deletions (indels) are more likely to influence complex traits than abundant single‐nucleotide polymorphisms (SNPs). We sought to understand which category of variation is more likely to impact health. Using the SardiNIA study as an exemplar, we characterized 478...

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Détails bibliographiques
Publié dans:Genet Epidemiol
Auteurs principaux: Gagliano, Sarah A., Sengupta, Sebanti, Sidore, Carlo, Maschio, Andrea, Cucca, Francesco, Schlessinger, David, Abecasis, Gonçalo R.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330128/
https://ncbi.nlm.nih.gov/pubmed/30565766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22175
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