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Low-coverage sequencing: Implications for design of complex trait association studies

New sequencing technologies allow genomic variation to be surveyed in much greater detail than previously possible. While detailed analysis of a single individual typically requires deep sequencing, when many individuals are sequenced it is possible to combine shallow sequence data across individual...

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Hlavní autoři: Li, Yun, Sidore, Carlo, Kang, Hyun Min, Boehnke, Michael, Abecasis, Gonçalo R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106327/
https://ncbi.nlm.nih.gov/pubmed/21460063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.117259.110
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