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Relative impact of indels versus SNPs on complex disease

It is unclear whether insertions and deletions (indels) are more likely to influence complex traits than abundant single‐nucleotide polymorphisms (SNPs). We sought to understand which category of variation is more likely to impact health. Using the SardiNIA study as an exemplar, we characterized 478...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Gagliano, Sarah A., Sengupta, Sebanti, Sidore, Carlo, Maschio, Andrea, Cucca, Francesco, Schlessinger, David, Abecasis, Gonçalo R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330128/
https://ncbi.nlm.nih.gov/pubmed/30565766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22175
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