A four-gene decision tree signature classification of triple-negative breast cancer: Implications for targeted therapeutics

The molecular complexity of triple-negative breast cancers (TNBCs) provides a challenge for patient management. We set out to characterise this heterogeneous disease by combining transcriptomics and genomics data, with the aim of revealing convergent pathway dependencies with the potential for treat...

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Veröffentlicht in:Mol Cancer Ther
Hauptverfasser: Quist, Jelmar, Mirza, Hasan, Cheang, Maggie C. U., Telli, Melinda L., O'Shaughnessy, Joyce A., Lord, Christopher J., Tutt, Andrew N. J., Grigoriadis, Anita
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330084/
https://ncbi.nlm.nih.gov/pubmed/30305342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-0243
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