A four-gene decision tree signature classification of triple-negative breast cancer: Implications for targeted therapeutics

The molecular complexity of triple-negative breast cancers (TNBCs) provides a challenge for patient management. We set out to characterise this heterogeneous disease by combining transcriptomics and genomics data, with the aim of revealing convergent pathway dependencies with the potential for treat...

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Pubblicato in:Mol Cancer Ther
Autori principali: Quist, Jelmar, Mirza, Hasan, Cheang, Maggie C. U., Telli, Melinda L., O'Shaughnessy, Joyce A., Lord, Christopher J., Tutt, Andrew N. J., Grigoriadis, Anita
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330084/
https://ncbi.nlm.nih.gov/pubmed/30305342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-0243
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