Genomic complexity profiling reveals that HORMAD1 overexpression contributes to homologous recombination deficiency in triple-negative breast cancers

Triple-negative breast cancers (TNBCs) are characterised by a wide spectrum of genomic alterations, some of which might be caused by defects in DNA repair processes such as homologous recombination (HR). Despite this understanding, associating particular patterns of genomic instability with response...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Discov
Main Authors: Watkins, Johnathan, Weekes, Daniel, Shah, Vandna, Gazinska, Patrycja, Joshi, Shalaka, Sidhu, Bhavna, Gillett, Cheryl, Pinder, Sarah, Vanoli, Fabio, Jasin, Maria, Mayrhofer, Markus, Isaksson, Anders, Cheang, Maggie C.U., Mirza, Hasan, Frankum, Jessica, Lord, Christopher J., Ashworth, Alan, Vinayak, Shaveta, Ford, James M., Telli, Melinda L., Grigoriadis, Anita, Tutt, Andrew N.J.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490184/
https://ncbi.nlm.nih.gov/pubmed/25770156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-14-1092
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki