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The Lec5 glycosylation mutant links homeobox genes with cholesterol and lipid-linked oligosaccharides

Discovered 40 years ago, the Lec5 glycosylation mutant cell line has a complex recessive genotype and is characterized by accumulation of lipid-linked oligosaccharide assembly intermediates, reduced conversion of polyprenols to dolichols, and an unusual phenotypic dependence upon cell culture condit...

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Pubblicato in:Glycobiology
Autori principali: Lu, Hua, Sathe, Adwait Amod, Xing, Chao, Lehrman, Mark A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330018/
https://ncbi.nlm.nih.gov/pubmed/30388226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwy103
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