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Analysis and metabolic engineering of lipid-linked oligosaccharides in glycosylation-deficient CHO cells

Glycosylation-deficient Chinese Hamster Ovary (CHO) cell lines can be used to expand our understanding of N-glycosylation pathways and to study Congenital Disorders of Glycosylation, diseases caused by defects in the synthesis of N-glycans. The mammalian N-glycosylation pathway involves the step-wis...

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Autors principals: Jones, Meredith B., Tomiya, Noboru, Betenbaugh, Michael J., Krag, Sharon S.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887678/
https://ncbi.nlm.nih.gov/pubmed/20331963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.03.117
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