Biomarkers for individualized dosage adjustments in immunosuppressive therapy using calcineurin inhibitors after organ transplantation

Calcineurin inhibitors (CNIs), such as cyclosporine A and tacrolimus, are widely used immunosuppressive agents for the prevention of post-transplantation rejection and have improved 1-year graft survival rates by up to 90%. However, CNIs can induce severe reactions, such as acute or chronic allograf...

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Dades bibliogràfiques
Publicat a:Acta Pharmacol Sin
Autors principals: Fu, Rao, Tajima, Soichiro, Suetsugu, Kimitaka, Watanabe, Hiroyuki, Egashira, Nobuaki, Masuda, Satohiro
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Review Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329804/
https://ncbi.nlm.nih.gov/pubmed/29950613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0070-2
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