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Caspase selective reagents for diagnosing apoptotic mechanisms

Apical caspases initiate and effector caspases execute apoptosis. Reagents that can distinguish between caspases, particularly apical caspases-8, 9, and 10 are scarce and generally nonspecific. Based upon a previously described large-scale screen of peptide-based caspase substrates termed HyCoSuL, w...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Poreba, Marcin, Groborz, Katarzyna, Navarro, Mario, Snipas, Scott J., Drag, Marcin, Salvesen, Guy S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329798/
https://ncbi.nlm.nih.gov/pubmed/29748600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0110-y
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