Pentatricopeptide repeat poly(A) binding protein KPAF4 stabilizes mitochondrial mRNAs in Trypanosoma brucei

In Trypanosoma brucei, most mitochondrial mRNAs undergo editing, and 3′ adenylation and uridylation. The internal sequence changes and terminal extensions are coordinated: pre-editing addition of the short (A) tail protects the edited transcript against 3′-5′ degradation, while post-editing A/U-tail...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Mesitov, Mikhail V., Yu, Tian, Suematsu, Takuma, Sement, Francois M., Zhang, Liye, Yu, Clinton, Huang, Lan, Aphasizheva, Inna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329795/
https://ncbi.nlm.nih.gov/pubmed/30635574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08137-2
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