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Transcription initiation defines kinetoplast RNA boundaries

Mitochondrial genomes are often transcribed into polycistronic RNAs punctuated by tRNAs whose excision defines mature RNA boundaries. Although kinetoplast DNA lacks tRNA genes, it is commonly held that in Trypanosoma brucei the monophosphorylated 5′ ends of functional molecules typify precursor part...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sement, François M., Suematsu, Takuma, Zhang, Liye, Yu, Tian, Huang, Lan, Aphasizheva, Inna, Aphasizhev, Ruslan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217428/
https://ncbi.nlm.nih.gov/pubmed/30333188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808981115
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