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Inhibition of cardiomyocyte Sprouty1 protects from cardiac ischemia–reperfusion injury

Sprouty1 (Spry1) is a negative modulator of receptor tyrosine kinase signaling, but its role in cardiomyocyte survival has not been elucidated. The aim of this study was to investigate the potential role of cardiomyocyte Spry1 in cardiac ischemia–reperfusion (I/R) injury. Infarct areas of mouse hear...

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Bibliographic Details
Published in:Basic Res Cardiol
Main Authors: Alakoski, Tarja, Ulvila, Johanna, Yrjölä, Raisa, Vainio, Laura, Magga, Johanna, Szabo, Zoltan, Licht, Jonathan D., Kerkelä, Risto
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329741/
https://ncbi.nlm.nih.gov/pubmed/30635790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-018-0713-y
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