Connective Tissue Growth Factor Inhibition Enhances Cardiac Repair and Limits Fibrosis After Myocardial Infarction

Myocardial infarction (MI)−induced cardiac fibrosis attenuates cardiac contractile function, and predisposes to arrhythmias and sudden cardiac death. Expression of connective tissue growth factor (CTGF) is elevated in affected organs in virtually every fibrotic disorder and in the diseased human myo...

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Dades bibliogràfiques
Publicat a:JACC Basic Transl Sci
Autors principals: Vainio, Laura E., Szabó, Zoltán, Lin, Ruizhu, Ulvila, Johanna, Yrjölä, Raisa, Alakoski, Tarja, Piuhola, Jarkko, Koch, Walter J., Ruskoaho, Heikki, Fouse, Shaun D., Seeley, Todd W., Gao, Erhe, Signore, Pierre, Lipson, Kenneth E., Magga, Johanna, Kerkelä, Risto
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
PRECLINICAL RESEARCH
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6390503/
https://ncbi.nlm.nih.gov/pubmed/30847422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.10.007
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