Systemic Blockade of ACVR2B Ligands Protects Myocardium from Acute Ischemia-Reperfusion Injury

Activin A and myostatin, members of the transforming growth factor (TGF)-β superfamily of secreted factors, are potent negative regulators of muscle growth, but their contribution to myocardial ischemia-reperfusion (IR) injury is not known. The aim of this study was to investigate if activin 2B (ACV...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Magga, Johanna, Vainio, Laura, Kilpiö, Teemu, Hulmi, Juha J., Taponen, Saija, Lin, Ruizhu, Räsänen, Markus, Szabó, Zoltán, Gao, Erhe, Rahtu-Korpela, Lea, Alakoski, Tarja, Ulvila, Johanna, Laitinen, Mika, Pasternack, Arja, Koch, Walter J., Alitalo, Kari, Kivelä, Riikka, Ritvos, Olli, Kerkelä, Risto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404100/
https://ncbi.nlm.nih.gov/pubmed/30765322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.01.013
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