Different mechanisms involved in liraglutide and glucagon‐like peptide‐1 vasodilatation in rat mesenteric small arteries

BACKGROUND AND PURPOSE: Glucagon‐like peptide‐1 (GLP‐1) is an incretin hormone that regulates insulin biosynthesis and secretion in a glucose‐dependent manner and has been reported to induce vasodilatation. Here, we examined the possible vasorelaxant effect of GLP‐1 and its underlying mechanisms. EX...

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Publicat a:Br J Pharmacol
Autors principals: Bangshaab, Maj, Gutierrez, Alejandro, Huynh, Khiem Dinh, Knudsen, Jakob Schöllhammer, Arcanjo, Daniel Dias Rufino, Petersen, Asbjørn G, Rungby, Jørgen, Gejl, Michael, Simonsen, Ulf
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329621/
https://ncbi.nlm.nih.gov/pubmed/30403290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14534
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