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CES1 genetic variation affects the activation of angiotensin-converting enzyme inhibitors
The aim of the study was to determine the effect of carboxylesterase 1(CES1) genetic variation on the activation of angiotensin-converting enzyme inhibitor (ACEI) prodrugs. In vitro incubation study of human liver, intestine, kidney s9 fractions demonstrated that the ACEI prodrugs enalapril, ramipri...
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| Izdano u: | Pharmacogenomics J |
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| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6329299/ https://ncbi.nlm.nih.gov/pubmed/26076923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2015.42 |
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