CES1 genetic variation affects the activation of angiotensin-converting enzyme inhibitors

The aim of the study was to determine the effect of carboxylesterase 1(CES1) genetic variation on the activation of angiotensin-converting enzyme inhibitor (ACEI) prodrugs. In vitro incubation study of human liver, intestine, kidney s9 fractions demonstrated that the ACEI prodrugs enalapril, ramipri...

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Foilsithe in:Pharmacogenomics J
Main Authors: Wang, Xinwen, Wang, Guangji, Shi, Jian, Aa, Jiye, Comas, Rinelly, Liang, Yan, Zhu, Hao-Jie
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329299/
https://ncbi.nlm.nih.gov/pubmed/26076923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2015.42
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