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Inhibiting STAT3 in a murine model of human breast cancer-induced bone pain delays the onset of nociception
Aggressive breast cancer subtypes utilize system x(c)(−), a membrane antiporter, to import cystine for glutathione synthesis and maintenance of redox homeostasis, in turn releasing glutamate as a metabolic pro-nociceptive by-product. Metastatic breast cancers establish themselves at distal sites inc...
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| Publicado no: | Mol Pain |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6329039/ https://ncbi.nlm.nih.gov/pubmed/30799695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806918823477 |
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