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Shifts in the selectivity filter dynamics cause modal gating in K(+) channels
Spontaneous activity shifts at constant experimental conditions represent a widespread regulatory mechanism in ion channels. The molecular origins of these modal gating shifts are poorly understood. In the K(+) channel KcsA, a multitude of fast activity shifts that emulate the native modal gating be...
Shranjeno v:
| izdano v: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6328603/ https://ncbi.nlm.nih.gov/pubmed/30631074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07973-6 |
| Oznake: |
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