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Shifts in the selectivity filter dynamics cause modal gating in K(+) channels
Spontaneous activity shifts at constant experimental conditions represent a widespread regulatory mechanism in ion channels. The molecular origins of these modal gating shifts are poorly understood. In the K(+) channel KcsA, a multitude of fast activity shifts that emulate the native modal gating be...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6328603/ https://ncbi.nlm.nih.gov/pubmed/30631074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07973-6 |
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