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Designing quorum sensing inhibitors of Pseudomonas aeruginosa utilizing FabI: an enzymic drug target from fatty acid synthesis pathway

Pseudomonas aeruginosa infections are a leading cause of death in patients suffering from respiratory diseases. The multidrug-resistant nature of Pseudomonas is potentiated by a process known as quorum sensing. The aim of this study was to reveal new inhibitors of a well-validated but quite unexplor...

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發表在:3 Biotech
Main Authors: Kalia, Manmohit, Yadav, Vivek Kumar, Singh, Pradeep Kumar, Dohare, Suhaga, Sharma, Deepmala, Narvi, Shahid Suhail, Agarwal, Vishnu
格式: Artigo
語言:Inglês
出版: Springer International Publishing 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328400/
https://ncbi.nlm.nih.gov/pubmed/30675450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-019-1567-1
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