The fatty acid synthesis gene fabY affects lipopolysaccharide synthesis and colistin susceptibility in Pseudomonas aeruginosa

ABSTRACT Bacterial metabolism impacts susceptibility to antibiotics. Here, we found that mutation of the Pseudomonas aeruginosa fatty acid response regulator gene pvrA decreases bacterial susceptibility to colistin. The fatty acid synthesis gene fabY is upregulated in the pvrA mutant. Deletion of fa...

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Bibliografiset tiedot

Päätekijät:	Dandan Zhou, Xiaoya Wei, Yongxin Jin, Zhihui Cheng, Shouguang Jin, Un-Hwan Ha, Xiaolei Pan, Weihui Wu
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology 2025-08-01
Sarja:	Microbiology Spectrum
Aiheet:	Pseudomonas aeruginosa fatty acid lipopolysaccharide colistin fabY
Linkit:	https://journals.asm.org/doi/10.1128/spectrum.01339-25
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