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Deletion of the β-Acetoacetyl Synthase FabY in Pseudomonas aeruginosa Induces Hypoacylation of Lipopolysaccharide and Increases Antimicrobial Susceptibility

The β-acetoacetyl-acyl carrier protein synthase FabY is a key enzyme in the initiation of fatty acid biosynthesis in Pseudomonas aeruginosa. Deletion of fabY results in an increased susceptibility of P. aeruginosa in vitro to a number of antibiotics, including vancomycin and cephalosporins. Because...

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Xehetasun bibliografikoak
Egile Nagusiak: Six, David A., Yuan, Yanqiu, Leeds, Jennifer A., Meredith, Timothy C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910788/
https://ncbi.nlm.nih.gov/pubmed/24145528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01804-13
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