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Designing antibody against highly conserved region of dengue envelope protein by in silico screening of scFv mutant library

Dengue being one of the deadliest diseases of tropical regions, enforces to put continuous efforts for the development of vaccine and effective therapeutics. Most of the antibodies generated during dengue infection are non-neutralizing and cause antibody dependent enhancement. Hence, making a potent...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS One
Main Authors: Rathore, Abhishek Singh, Sarker, Animesh, Gupta, Rinkoo Devi
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328183/
https://ncbi.nlm.nih.gov/pubmed/30629625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209576
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