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Designing antibody against highly conserved region of dengue envelope protein by in silico screening of scFv mutant library

Dengue being one of the deadliest diseases of tropical regions, enforces to put continuous efforts for the development of vaccine and effective therapeutics. Most of the antibodies generated during dengue infection are non-neutralizing and cause antibody dependent enhancement. Hence, making a potent...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rathore, Abhishek Singh, Sarker, Animesh, Gupta, Rinkoo Devi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328183/
https://ncbi.nlm.nih.gov/pubmed/30629625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209576
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