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ERK-mediated TIMELESS expression suppresses G2/M arrest in colon cancer cells
The cell cycle is under circadian regulation. Oncogenes can dysregulate circadian-regulated genes to disrupt the cell cycle, promoting tumor cell proliferation. As a regulator of G2/M arrest in response to DNA damage, the circadian gene Timeless Circadian Clock (TIMELESS) coordinates this connection...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6328106/ https://ncbi.nlm.nih.gov/pubmed/30629587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209224 |
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