Prostate cancer cells and exosomes in acidic condition show increased carbonic anhydrase IX expression and activity

Acidity and hypoxia are crucial phenotypes of tumour microenvironment both contributing to the selection of malignant cells under a micro evolutionistic pressure. During the tumour progression, nanovesicles, called exosomes and the metalloenzyme carbonic anhydrase IX (CA IX) affect the tumour growth...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Logozzi, Mariantonia, Capasso, Clemente, Di Raimo, Rossella, Del Prete, Sonia, Mizzoni, Davide, Falchi, Mario, Supuran, Claudiu T., Fais, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327996/
https://ncbi.nlm.nih.gov/pubmed/30734594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1538980
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